Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MCPH1 (263-562) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MCPH1 |
Gene ID: |
79648 |
Uniprot ID: |
MCPH1_HUMAN |
Immunogen Region: |
263-562 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 263-562 of human MCPH1 (NP_001166046.1). |
Immunogen Sequence: |
VTPDQKQAAGMSQETFEEKY RLSPTLSSTKGHLLIHSRPR SSSVKRKRVSHGSHSPPKEK CKRKRSTRRSIMPRLQLCRS EDRLQHVAGPALEALSCGES SYDDYFSPDNLKERYSENLP PESQLPSSPAQLSCRSLSKK ERTSIFEMSDFSCVGKKTRT VDITNFTAKTISSPRKTGNG EGRATSSCVTSAPEEALRCC RQAGKEDACPEGNGFSYTIE DPALPKGHDDDLTPLEGSL |
Tissue Specificity | Expressed in fetal brain, liver and kidney. |
Function | Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex. |
Protein Name | Microcephalin |
Database Links | Reactome: R-HSA-2299718 |
Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
Alternative Antibody Names | Anti-Microcephalin antibodyAnti-MCPH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance