• STJ70555 staining (1µg/ml) of Human Lung lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Anti-MCL1 antibody (C-Term) (STJ70555)

SKU:
STJ70555-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-MCL1 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:2000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: MCL1
Gene ID: 4170
Uniprot ID: MCL1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_068779.1; NP_001184249.1
Specificity: This antibody is expected to recognise reported isoform 1 (NP_068779.1) and isoform 3 (NP_001184249.1).
Immunogen Sequence: AGVGAGLAYLIR
Function Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Protein Name Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
Bcl-2-Like Protein 3
Bcl2-L-3
Bcl-2-Related Protein Eat/Mcl1
Mcl1/Eat
Database Links Reactome: R-HSA-6785807
Cellular Localisation Membrane
Single-Pass Membrane Protein
Cytoplasm
Mitochondrion
Nucleus
Nucleoplasm
Cytoplasmic
Associated With Mitochondria
Alternative Antibody Names Anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 antibody
Anti-Bcl-2-Like Protein 3 antibody
Anti-Bcl2-L-3 antibody
Anti-Bcl-2-Related Protein Eat/Mcl1 antibody
Anti-Mcl1/Eat antibody
Anti-MCL1 antibody
Anti-BCL2L3 antibody

Information sourced from Uniprot.org

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