| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MCHR1 |
| Gene ID: | 2847 |
| Uniprot ID: | MCHR1_HUMAN |
| Immunogen Region: | 1-95 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human MCHR1 (NP_005288.3). |
| Immunogen Sequence: | MSVGAMKKGVGRAVGLGGGS GCQATEEDPLPNCGACAPGQ GGRRWRLPQPAWVEGSSARL WEQATGTGWMDLEASLLPTG PNASNTSDGPDNLTS |
| Tissue Specificity | Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. |
| Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. |
| Protein Name | Melanin-Concentrating Hormone Receptor 1 Mch Receptor 1 Mch-R1 Mchr-1 G-Protein Coupled Receptor 24 Mch-1r Mch1r Mchr Slc-1 Somatostatin Receptor-Like Protein |
| Database Links | Reactome: R-HSA-375276 Reactome: R-HSA-416476 Reactome: R-HSA-418594 Reactome: R-HSA-5620922 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melanin-Concentrating Hormone Receptor 1 antibody Anti-Mch Receptor 1 antibody Anti-Mch-R1 antibody Anti-Mchr-1 antibody Anti-G-Protein Coupled Receptor 24 antibody Anti-Mch-1r antibody Anti-Mch1r antibody Anti-Mchr antibody Anti-Slc-1 antibody Anti-Somatostatin Receptor-Like Protein antibody Anti-MCHR1 antibody Anti-GPR24 antibody Anti-SLC1 antibody |
Information sourced from Uniprot.org