| Short Description : | Humanized monoclonal anti-Matuzumab-EGFR for use in FUNC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FUNC |
| Host: | Humanized |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | Affinity Purified |
| Formulation: | 0.01M PBS, pH 7.2 |
| Storage Instruction: | This solution is stable for at least 4 weeks when stored at 2-8°C. For long term storage aseptically aliquot and store at –80°C. Avoid repeated freeze/thaw cycles. |
| Background | Matuzumab biosimilar is a humanized IgG1 monoclonal antibody against human EGFR. As it only has approximately 10% murine origin it has limited immunogenicity, and being IgG1 it is capable of inducing antibody dependent cell cytotoxicity (ADCC). |
Information sourced from Uniprot.org
