| Tissue Specificity | Expressed in liver. |
| Post Translational Modifications | S-nitrosylation of Cys-120 inactivates the enzyme. An intrachain disulfide bond can be formed. The protein structure shows that the relevant Cys residues are in a position that would permit formation of a disulfide bond. |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Protein Name | S-Adenosylmethionine Synthase Isoform Type-1Adomet Synthase 1Methionine Adenosyltransferase 1Mat 1Methionine Adenosyltransferase I/IiiMat-I/Iii |
| Database Links | Reactome: R-HSA-156581Reactome: R-HSA-1614635Reactome: R-HSA-2408508Reactome: R-HSA-5579024 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-S-Adenosylmethionine Synthase Isoform Type-1 antibodyAnti-Adomet Synthase 1 antibodyAnti-Methionine Adenosyltransferase 1 antibodyAnti-Mat 1 antibodyAnti-Methionine Adenosyltransferase I/Iii antibodyAnti-Mat-I/Iii antibodyAnti-MAT1A antibodyAnti-AMS1 antibodyAnti-MATA1 antibody |
Information sourced from Uniprot.org
