| Tissue Specificity | Abundant in the testis. |
| Post Translational Modifications | Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination. |
| Function | Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation. |
| Protein Name | Microtubule-Associated Serine/Threonine-Protein Kinase 2 |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic SideRecruited To The Sub-Membranous Area On Interaction With Cdhr2 |
| Alternative Antibody Names | Anti-Microtubule-Associated Serine/Threonine-Protein Kinase 2 antibodyAnti-MAST2 antibodyAnti-KIAA0807 antibodyAnti-MAST205 antibody |
Information sourced from Uniprot.org
