Anti-MAST2 antibody (1201-1250 aa) (STJ94023)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MAST2 at the amino acid range 1201-1250
General Information
| Short Description | Rabbit polyclonal anti-Microtubule-associated serine/threonine-protein kinase 2 (1201-1250 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAST2 |
| Gene ID | 23139 |
| Uniprot ID | MAST2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MAST2 at the amino acid range 1201-1250 |
| Immunogen Region | 1201-1250 aa |
| Specificity | MAST205 Polyclonal Antibody detects endogenous levels of MAST205 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination. |
| Function | Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation. |
| Protein Name | Microtubule-Associated Serine/Threonine-Protein Kinase 2 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic SideRecruited To The Sub-Membranous Area On Interaction With Cdhr2 |
| Alternative Antibody Names | Anti-Microtubule-Associated Serine/Threonine-Protein Kinase 2 antibodyAnti-MAST2 antibodyAnti-KIAA0807 antibodyAnti-MAST205 antibody |
Information sourced from Uniprot.org