• Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-MARCKSL1 antibody (1-80 aa) (STJ190198)

SKU:
STJ190198

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MARCKS-related protein (1-80 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MARCKSL1
Gene ID: 65108
Uniprot ID: MRP_HUMAN
Immunogen Region: 1-80 aa
Specificity: MRP Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 1-80
Function Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems.
Protein Name Marcks-Related Protein
Marcks-Like Protein 1
Macrophage Myristoylated Alanine-Rich C Kinase Substrate
Mac-Marcks
Macmarcks
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Membrane
Lipid-Anchor
Associates With The Membrane Via The Insertion Of The N-Terminal N-Myristoyl Chain And The Partial Insertion Of The Effector Domain
Association Of The Effector Domain With Membranes May Be Regulated By Ca(2+)/Calmodulin
Colocalizes With F-Actin At The Leading Edge Of Migrating Cells
In Prostate Cancers
Shows Strong Expression At Apical And/Or Basal Regions Of The Cell And Also Has Weak Cytoplasmic Expression
Alternative Antibody Names Anti-Marcks-Related Protein antibody
Anti-Marcks-Like Protein 1 antibody
Anti-Macrophage Myristoylated Alanine-Rich C Kinase Substrate antibody
Anti-Mac-Marcks antibody
Anti-Macmarcks antibody
Anti-MARCKSL1 antibody
Anti-MLP antibody
Anti-MRP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance