Anti-MARCHF4 antibody (301-350 aa) (STJ94010)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MARCH4 at the amino acid range 301-350
General Information
| Short Description | Rabbit polyclonal anti-E3 ubiquitin-protein ligase MARCHF4 (301-350 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MARCHF4 |
| Gene ID | 57574 |
| Uniprot ID | MARH4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MARCH4 at the amino acid range 301-350 |
| Immunogen Region | 301-350 aa |
| Specificity | MARCH4 Polyclonal Antibody detects endogenous levels of 40606 protein. |
Additional Info
| Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Protein Name | E3 Ubiquitin-Protein Ligase Marchf4Membrane-Associated Ring Finger Protein 4Membrane-Associated Ring-Ch Protein IvMarch-IvRing Finger Protein 174Ring-Type E3 Ubiquitin Transferase Marchf4 |
| Database Links | |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf4 antibodyAnti-Membrane-Associated Ring Finger Protein 4 antibodyAnti-Membrane-Associated Ring-Ch Protein Iv antibodyAnti-March-Iv antibodyAnti-Ring Finger Protein 174 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf4 antibodyAnti-MARCHF4 antibodyAnti-KIAA1399 antibodyAnti-MARCH4 antibodyAnti-RNF174 antibody |
Information sourced from Uniprot.org