| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-MARCH-IV (Internal) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:4000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
MARCHF4 |
| Gene ID: |
57574 |
| Uniprot ID: |
MARH4_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_065865.1 |
| Immunogen Sequence: |
DFCKEKTEDRYS |
| Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Protein Name | E3 Ubiquitin-Protein Ligase Marchf4Membrane-Associated Ring Finger Protein 4Membrane-Associated Ring-Ch Protein IvMarch-IvRing Finger Protein 174Ring-Type E3 Ubiquitin Transferase Marchf4 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf4 antibodyAnti-Membrane-Associated Ring Finger Protein 4 antibodyAnti-Membrane-Associated Ring-Ch Protein Iv antibodyAnti-March-Iv antibodyAnti-Ring Finger Protein 174 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf4 antibodyAnti-MARCHF4 antibodyAnti-KIAA1399 antibodyAnti-MARCH4 antibodyAnti-RNF174 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
