Anti-MAPK8IP2 antibody (581-630 aa) (STJ93800)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human JIP2 at the amino acid range 581-630
General Information
| Short Description | Rabbit polyclonal anti-C-Jun-amino-terminal kinase-interacting protein 2 (581-630 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAPK8IP2 |
| Gene ID | 23542 |
| Uniprot ID | JIP2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human JIP2 at the amino acid range 581-630 |
| Immunogen Region | 581-630 aa |
| Specificity | JIP-2 Polyclonal Antibody detects endogenous levels of JIP-2 protein. |
Additional Info
| Function | The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. |
| Protein Name | C-Jun-Amino-Terminal Kinase-Interacting Protein 2Jip-2Jnk-Interacting Protein 2Islet-Brain-2Ib-2Jnk Map Kinase Scaffold Protein 2Mitogen-Activated Protein Kinase 8-Interacting Protein 2 |
| Database Links | |
| Cellular Localisation | CytoplasmAccumulates In Cell Surface Projections |
| Alternative Antibody Names | Anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 antibodyAnti-Jip-2 antibodyAnti-Jnk-Interacting Protein 2 antibodyAnti-Islet-Brain-2 antibodyAnti-Ib-2 antibodyAnti-Jnk Map Kinase Scaffold Protein 2 antibodyAnti-Mitogen-Activated Protein Kinase 8-Interacting Protein 2 antibodyAnti-MAPK8IP2 antibodyAnti-IB2 antibodyAnti-JIP2 antibodyAnti-PRKM8IPL antibody |
Information sourced from Uniprot.org