Host: | Rabbit |
Applications: | ELISA/IHC/IP/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-MAP3K4 (1558-1608) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
Purification: | Affinity Purified |
Concentration: | 0.50 µg/µl |
Dilution Range: | WB: 1:500ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:100 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | MAP3K4 |
Gene ID: | 4216 |
Uniprot ID: | M3K4_HUMAN |
Immunogen Region: | 1558-1608 |
Immunogen: | Synthetic peptide taken within amino acid region 1558-1608 on human MAP3K4 protein. |
Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues. |
Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 antibodyAnti-Map Three Kinase 1 antibodyAnti-Mapk/Erk Kinase Kinase 4 antibodyAnti-Mek Kinase 4 antibodyAnti-Mekk 4 antibodyAnti-MAP3K4 antibodyAnti-KIAA0213 antibodyAnti-MAPKKK4 antibodyAnti-MEKK4 antibodyAnti-MTK1 antibody |
Information sourced from Uniprot.org