| Short Description : | Rabbit polyclonal anti-Mitogen-activated protein kinase kinase kinase 4 (1281-1330 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAP3K4 |
| Gene ID: | 4216 |
| Uniprot ID: | M3K4_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MAP3K4 at the amino acid range 1281-1330 |
| Immunogen Region: | 1281-1330 aa |
| Specificity: | MEK Kinase-4 Polyclonal Antibody detects endogenous levels of MEK Kinase-4 protein. |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 4Map Three Kinase 1Mapk/Erk Kinase Kinase 4Mek Kinase 4Mekk 4 |
| Database Links | |
| Cellular Localisation | CytoplasmPerinuclear RegionLocalized In Perinuclear Vesicular-Like StructuresProbably Golgi-Associated Vesicles |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 antibodyAnti-Map Three Kinase 1 antibodyAnti-Mapk/Erk Kinase Kinase 4 antibodyAnti-Mek Kinase 4 antibodyAnti-Mekk 4 antibodyAnti-MAP3K4 antibodyAnti-KIAA0213 antibodyAnti-MAPKKK4 antibodyAnti-MEKK4 antibodyAnti-MTK1 antibody |
Information sourced from Uniprot.org
