Anti-MAP3K3 antibody (1-100) [S0MR] (STJ11101930)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MEKK3 (1-100) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S0MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAP3K3 |
| Gene ID | 4215 |
| Uniprot ID | M3K3_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MDEQEALNSIMNDLVALQMN RRHRMPGYETMKNKDTGHSN RQSDVRIKFEHNGERRIIAF SRPVKYEDVEHKVTTVFGQP LDLHYMNNELSILLKNQDDL |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEKK3 (Q99759). |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-166 and Ser-337 by SGK1 inhibits its activity. |
| Function | Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 3Mapk/Erk Kinase Kinase 3Mek Kinase 3Mekk 3 |
| Database Links | Reactome: R-HSA-9020702 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 antibodyAnti-Mapk/Erk Kinase Kinase 3 antibodyAnti-Mek Kinase 3 antibodyAnti-Mekk 3 antibodyAnti-MAP3K3 antibodyAnti-MAPKKK3 antibodyAnti-MEKK3 antibody |
Information sourced from Uniprot.org