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Anti-MAP3K1 antibody [EBS-T-008] (STJ16101082)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenA BALB/c mouse was immunized with partial recombinant MAP3K1 (aa1211-1310). Fusion partner: Sp2/0.
General Information
| Short Description | Mouse monoclonal anti-MAP3K1 for use in ELISA, FC, WB and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC/WB/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | EBS-T-008 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Flow Cytometry (0, 5-1 µg/million cells in 0.1 ml). Immunoblotting (0, 5-1 µg/ml). Immunohistology (0, 5-1, 0 µg/ml for 30 minutes at RT; Staining of formalin-fixed tissu |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Gene Symbol | MAP3K1 |
| Gene ID | 4214 |
| Uniprot ID | M3K1_HUMAN |
| Immunogen | A BALB/c mouse was immunized with partial recombinant MAP3K1 (aa1211-1310). Fusion partner: Sp2/0. |
Additional Info
| Post Translational Modifications | Autophosphorylated. |
| Function | Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 1Mapk/Erk Kinase Kinase 1Mek Kinase 1Mekk 1 |
| Database Links | Reactome: R-HSA-166058Reactome: R-HSA-2871796Reactome: R-HSA-933542Reactome: R-HSA-975138Reactome: R-HSA-975871 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 antibodyAnti-Mapk/Erk Kinase Kinase 1 antibodyAnti-Mek Kinase 1 antibodyAnti-Mekk 1 antibodyAnti-MAP3K1 antibodyAnti-MAPKKK1 antibodyAnti-MEKK antibodyAnti-MEKK1 antibody |
Information sourced from Uniprot.org