Anti-Mannose Receptor antibody [R06-5I1] (STJA0034541)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Mannose Receptor
General Information
| Short Description | Rabbit monoclonal anti-Mannose Receptor for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-5I1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MRC1 |
| Gene ID | 4360 |
| Uniprot ID | MRC1_HUMAN |
| Immunogen | A synthetic peptide of human Mannose Receptor |
Additional Info
| Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein. |
| Protein Name | Macrophage Mannose Receptor 1MmrC-Type Lectin Domain Family 13 Member DC-Type Lectin Domain Family 13 Member D-LikeHuman Mannose ReceptorHmrMacrophage Mannose Receptor 1-Like Protein 1Cd Antigen Cd206 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-9637628 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Macrophage Mannose Receptor 1 antibodyAnti-Mmr antibodyAnti-C-Type Lectin Domain Family 13 Member D antibodyAnti-C-Type Lectin Domain Family 13 Member D-Like antibodyAnti-Human Mannose Receptor antibodyAnti-Hmr antibodyAnti-Macrophage Mannose Receptor 1-Like Protein 1 antibodyAnti-Cd Antigen Cd206 antibodyAnti-MRC1 antibodyAnti-CLEC13D antibodyAnti-CLEC13DL antibodyAnti-MRC1L1 antibody |
Information sourced from Uniprot.org