| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MANBA |
| Gene ID: | 4126 |
| Uniprot ID: | MANBA_HUMAN |
| Immunogen Region: | 18-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-300 of human MANBA (NP_005899.3). |
| Immunogen Sequence: | AAELSYSLRGNWSICNGNGS LELPGAVPGCVHSALFQQGL IQDSYYRFNDLNYRWVSLDN WTYSKEFKIPFEISKWQKVN LILEGVDTVSKILFNEVTIG ETDNMFNRYSFDITNVVRDV NSIELRFQSAVLYAAQQSKA HTRYQVPPDCPPLVQKGECH VNFVRKEQCSFSWDWGPSFP TQGIWKDVRIEAYNICHLNY FTFSPIYDKSAQEWNLEIES TFDVVSSKPVGGQVIVAIP |
| Tissue Specificity | Ubiquitous. Detected in pancreas, kidney and placenta, ands at lower levels in liver, lung, brain, heart and muscle. |
| Function | Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. |
| Protein Name | Beta-MannosidaseLysosomal Beta A MannosidaseMannanaseMannase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8853383 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Beta-Mannosidase antibodyAnti-Lysosomal Beta A Mannosidase antibodyAnti-Mannanase antibodyAnti-Mannase antibodyAnti-MANBA antibodyAnti-MANB1 antibody |
Information sourced from Uniprot.org