| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAN2A1 |
| Gene ID: | 4124 |
| Uniprot ID: | MA2A1_HUMAN |
| Immunogen Region: | 865-1144 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 865-1144 of human MAN2A1 (NP_002363.2). |
| Immunogen Sequence: | SNIVDIRKVYNREIAMKISS DIKSQNRFYTDLNGYQIQPR MTLSKLPLQANVYPMTTMAY IQDAKHRLTLLSAQSLGVSS LNSGQIEVIMDRRLMQDDNR GLEQGIQDNKITANLFRILL EKRSAVNTEEEKKSVSYPSL LSHITSSLMNHPVIPMANKF SSPTLELQGEFSPLQSSLPC DIHLVNLRTIQSKVGNGHSN EAALILHRKGFDCRFSSKGT GLFCSTTQGKILVQKLLNK |
| Post Translational Modifications | Glycosylated. |
| Function | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans.the final hydrolytic step in the N-glycan maturation pathway. |
| Protein Name | Alpha-Mannosidase 2Golgi Alpha-Mannosidase IiAman IiMan IiMannosidase Alpha Class 2a Member 1Mannosyl-Oligosaccharide 1 -3-1 -6-Alpha-Mannosidase |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-9694548Reactome: R-HSA-975578 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-Mannosidase 2 antibodyAnti-Golgi Alpha-Mannosidase Ii antibodyAnti-Aman Ii antibodyAnti-Man Ii antibodyAnti-Mannosidase Alpha Class 2a Member 1 antibodyAnti-Mannosyl-Oligosaccharide 1 -3-1 -6-Alpha-Mannosidase antibodyAnti-MAN2A1 antibodyAnti-MANA2 antibody |
Information sourced from Uniprot.org