Anti-MAN1C1 antibody (44-240) (STJ114703)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MAN1C1 (44-240) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAN1C1 |
| Gene ID | 57134 |
| Uniprot ID | MA1C1_HUMAN |
| Immunogen Region | 44-240 |
| Immunogen Sequence | PHSSRLKRLFLAPRTQQPGL EVVAEIAGHAPAREQEPPPN PAPAAPAPGEDDPSSWASPR RRKGGLRRTRPTGPREEATA ARGNSIPASRPGDEGVPFRF DFNAFRSRLRHPVLGTRADE SQEPQSQVRAQREKIKEMMQ FAWQSYKRYAMGKNELRPLT KDGYEGNMFGGLSGATVIDS LDTLYLMELKEEFQEAK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1). |
Additional Info
| Tissue Specificity | Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta. |
| Function | Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. |
| Protein Name | Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase IcHmicMannosidase Alpha Class 1c Member 1Processing Alpha-1 -2-Mannosidase IcAlpha-1 -2-Mannosidase Ic |
| Database Links | Reactome: R-HSA-6811438Reactome: R-HSA-964827 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase Ic antibodyAnti-Hmic antibodyAnti-Mannosidase Alpha Class 1c Member 1 antibodyAnti-Processing Alpha-1 -2-Mannosidase Ic antibodyAnti-Alpha-1 -2-Mannosidase Ic antibodyAnti-MAN1C1 antibodyAnti-MAN1A3 antibodyAnti-MAN1C antibody |
Information sourced from Uniprot.org