• Immunofluorescence analysis of C6 cells using MAML2 Rabbit polyclonal antibody (STJ11102886) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using MAML2 Rabbit polyclonal antibody (STJ11102886) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-MAML2 antibody (750-850) (STJ11102886)

SKU:
STJ11102886

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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MAML2 (750-850) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAML2
Gene ID: 84441
Uniprot ID: MAML2_HUMAN
Immunogen Region: 750-850
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human MAML2 (NP_115803.1).
Immunogen Sequence: NQQLMGKKQTLQRQIMEQKQ QLLLQQQMLADAEKIAPQDQ INRHLSRPPPDYKDQRRNVG NMQPTAQYSGGSSTISLNSN QALANPVSTHTILTPNSSLL S
Tissue Specificity Widely expressed with high levels detected in placenta, salivary gland and skeletal muscle.
Function Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
Protein Name Mastermind-Like Protein 2
Mam-2
Database Links Reactome: R-HSA-1912408
Reactome: R-HSA-210744
Reactome: R-HSA-2122947
Reactome: R-HSA-2197563
Reactome: R-HSA-2644606
Reactome: R-HSA-2894862
Reactome: R-HSA-350054
Reactome: R-HSA-8941856
Reactome: R-HSA-9013508
Reactome: R-HSA-9013695
Reactome: R-HSA-9793380
Cellular Localisation Nucleus Speckle
Nuclear
In A Punctate Manner
Alternative Antibody Names Anti-Mastermind-Like Protein 2 antibody
Anti-Mam-2 antibody
Anti-MAML2 antibody
Anti-KIAA1819 antibody

Information sourced from Uniprot.org

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