Western blot analysis of MAGEC2 Antibody. The lane on the right is blocked with the MAGEC2 peptide.

Anti-MAGEC2 antibody (160-240 aa) (STJ93991)

SKU:
STJ93991
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Melanoma-associated antigen C2 (160-240 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAGEC2
Gene ID: 51438
Uniprot ID: MAGC2_HUMAN
Immunogen Region: 160-240 aa
Specificity: MAGE-C2 Polyclonal Antibody detects endogenous levels of MAGE-C2 protein.
Immunogen: Synthesized peptide derived from MAGE-C2 at the amino acid range 160-240
Function Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Protein Name Melanoma-Associated Antigen C2
Cancer/Testis Antigen 10
Ct10
Hepatocellular Carcinoma-Associated Antigen 587
Mage-C2 Antigen
Mage-E1 Antigen
Cellular Localisation Cytoplasm
Nucleus
Nuclear In Germ Cells
Cytoplasmic In Well-Differentiated Hepatocellular Carcinoma
Nuclear In Moderately- And Poorly-Differentiated Hepatocellular Carcinoma
Alternative Antibody Names Anti-Melanoma-Associated Antigen C2 antibody
Anti-Cancer/Testis Antigen 10 antibody
Anti-Ct10 antibody
Anti-Hepatocellular Carcinoma-Associated Antigen 587 antibody
Anti-Mage-C2 Antigen antibody
Anti-Mage-E1 Antigen antibody
Anti-MAGEC2 antibody
Anti-HCA587 antibody
Anti-MAGEE1 antibody

Information sourced from Uniprot.org

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