| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Melanoma-associated antigen C2 (160-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAGEC2 |
| Gene ID: |
51438 |
| Uniprot ID: |
MAGC2_HUMAN |
| Immunogen Region: |
160-240 aa |
| Specificity: |
MAGE-C2 Polyclonal Antibody detects endogenous levels of MAGE-C2 protein. |
| Immunogen: |
Synthesized peptide derived from MAGE-C2 at the amino acid range 160-240 |
| Function | Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. |
| Protein Name | Melanoma-Associated Antigen C2Cancer/Testis Antigen 10Ct10Hepatocellular Carcinoma-Associated Antigen 587Mage-C2 AntigenMage-E1 Antigen |
| Cellular Localisation | CytoplasmNucleusNuclear In Germ CellsCytoplasmic In Well-Differentiated Hepatocellular CarcinomaNuclear In Moderately- And Poorly-Differentiated Hepatocellular Carcinoma |
| Alternative Antibody Names | Anti-Melanoma-Associated Antigen C2 antibodyAnti-Cancer/Testis Antigen 10 antibodyAnti-Ct10 antibodyAnti-Hepatocellular Carcinoma-Associated Antigen 587 antibodyAnti-Mage-C2 Antigen antibodyAnti-Mage-E1 Antigen antibodyAnti-MAGEC2 antibodyAnti-HCA587 antibodyAnti-MAGEE1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
