Anti-MAD3/MXD3 antibody (100-190) [S8MR] (STJ11103148)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MAD3/MXD3 (100-190) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S8MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MXD3 |
| Gene ID | 83463 |
| Uniprot ID | MAD3_HUMAN |
| Immunogen Region | 100-190 |
| Immunogen Sequence | RRARMHIQKLEDQEQRARQL KERLRSKQQSLQRQLEQLRG LAGAAERERLRADSLDSSGL SSERSDSDQEELEVDVESLV FGGEAELLRGF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 100-190 of human MAD3/MXD3 (Q9BW11). |
Additional Info
| Function | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. |
| Protein Name | Max Dimerization Protein 3Max Dimerizer 3Class C Basic Helix-Loop-Helix Protein 13Bhlhc13Max-Associated Protein 3Max-Interacting Transcriptional Repressor Mad3Myx |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max Dimerization Protein 3 antibodyAnti-Max Dimerizer 3 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 13 antibodyAnti-Bhlhc13 antibodyAnti-Max-Associated Protein 3 antibodyAnti-Max-Interacting Transcriptional Repressor Mad3 antibodyAnti-Myx antibodyAnti-MXD3 antibodyAnti-BHLHC13 antibodyAnti-MAD3 antibody |
Information sourced from Uniprot.org