Anti-MACC1 antibody (411-460 aa) (STJ96657)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human MACC1 at the amino acid range 411-460
General Information
| Short Description | Rabbit polyclonal anti-Metastasis-associated in colon cancer protein 1 (411-460 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MACC1 |
| Gene ID | 346389 |
| Uniprot ID | MACC1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1 at the amino acid range 411-460 |
| Immunogen Region | 411-460 aa |
| Specificity | MACC1 Polyclonal Antibody detects endogenous levels of MACC1 protein. |
Additional Info
| Function | Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. |
| Protein Name | Metastasis-Associated In Colon Cancer Protein 1Sh3 Domain-Containing Protein 7a5 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusMainly Found In The Cytoplasm In Non-Metastasizing Tumors |
| Alternative Antibody Names | Anti-Metastasis-Associated In Colon Cancer Protein 1 antibodyAnti-Sh3 Domain-Containing Protein 7a5 antibodyAnti-MACC1 antibody |
Information sourced from Uniprot.org