Tissue Specificity | Expressed in prostate, ovary, stomach, pancreas, esophagus, breast, liver, bladder, kidney, thyroid, colon and lung (at protein level). Down-regulated in multiple primary tumors (at protein level). Detected in testis, heart, skeletal muscle, thymus, spleen, small intestine, and peripheral blood leukocytes. |
Function | Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function. |
Protein Name | Leucine Zipper Transcription Factor-Like Protein 1 |
Database Links | Reactome: R-HSA-5620922 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Leucine Zipper Transcription Factor-Like Protein 1 antibodyAnti-LZTFL1 antibody |
Information sourced from Uniprot.org