| Tissue Specificity | Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. |
| Post Translational Modifications | N-glycosylated and O-glycosylated. |
| Function | Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression. |
| Protein Name | Ly6/Plaur Domain-Containing Protein 3Gpi-Anchored Metastasis-Associated Protein C4.4a HomologMatrigel-Induced Gene C4 ProteinMig-C4 |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Ly6/Plaur Domain-Containing Protein 3 antibodyAnti-Gpi-Anchored Metastasis-Associated Protein C4.4a Homolog antibodyAnti-Matrigel-Induced Gene C4 Protein antibodyAnti-Mig-C4 antibodyAnti-LYPD3 antibodyAnti-C4.4A antibodyAnti-UNQ491 antibodyAnti-PRO1007 antibody |
Information sourced from Uniprot.org
