Anti-LY86 antibody (50-150) (STJ11102840)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LY86 (50-150) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LY86 |
| Gene ID | 9450 |
| Uniprot ID | LY86_HUMAN |
| Immunogen Region | 50-150 |
| Immunogen Sequence | DFGFSVEKCSKQLKSNINIR FGIILREDIKELFLDLALMS QGSSVLNFSYPICEAALPKF SFCGRRKGEQIYYAGPVNNP EFTIPQGEYQVLLELYTEKR S |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human LY86 (NP_004262.1). |
Additional Info
| Tissue Specificity | Highly expressed in B-cells, monocytes and tonsil. |
| Function | May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. |
| Protein Name | Lymphocyte Antigen 86Ly-86Protein Md-1 |
| Database Links | Reactome: R-HSA-166016 |
| Cellular Localisation | SecretedExtracellular SpaceAssociated With Cd180 At The Cell Surface |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 86 antibodyAnti-Ly-86 antibodyAnti-Protein Md-1 antibodyAnti-LY86 antibodyAnti-MD1 antibody |
Information sourced from Uniprot.org