| Short Description : | Rabbit polyclonal LY86 (21-162) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LY86 |
| Gene ID: | 9450 |
| Uniprot ID: | LY86_HUMAN |
| Immunogen Region: | 21-162 |
| Immunogen Sequence: | GGGGKAWPTHVVCSDSGLEV LYQSCDPLQDFGFSVEKCSK QLKSNINIRFGIILREDIKE LFLDLALMSQGSSVLNFSYP ICEAALPKFSFCGRRKGEQI YYAGPVNNPEFTIPQGEYQV LLELYTEKRSTVACANATIM CS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-162 of human LY86 (NP_004262.1). |
| Tissue Specificity | Highly expressed in B-cells, monocytes and tonsil. |
| Function | May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. |
| Protein Name | Lymphocyte Antigen 86Ly-86Protein Md-1 |
| Database Links | Reactome: R-HSA-166016 |
| Cellular Localisation | SecretedExtracellular SpaceAssociated With Cd180 At The Cell Surface |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 86 antibodyAnti-Ly-86 antibodyAnti-Protein Md-1 antibodyAnti-LY86 antibodyAnti-MD1 antibody |
Information sourced from Uniprot.org
