| Short Description : | Mouse monoclonal Lymphocyte antigen 6h antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/FC |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 12G7 |
| Isotype: | IgG2ak |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/ml |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Formulation: | 0.01M PBS, pH 7.4, 0.09% Sodium azide. |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | LY6H |
| Gene ID: | 4062 |
| Uniprot ID: | LY6H_HUMAN |
| Function | Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons. |
| Protein Name | Lymphocyte Antigen 6hLy-6h |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 6h antibodyAnti-Ly-6h antibodyAnti-LY6H antibody |
Information sourced from Uniprot.org