Host: | Mouse |
Applications: | ELISA/FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Short Description : | Mouse monoclonal antibody anti-Lymphocyte antigen 6h is suitable for use in ELISA and Flow Cytometry research applications. |
Clonality : | Monoclonal |
Clone ID : | 12G7 |
Conjugation: | FITC |
Isotype: | IgG2ak |
Formulation: | 0.01M PBS, pH 7.4, 02% BSA, 0.05% Proclin 300 |
Purification: | Purified |
Concentration: | 05 mg/mL |
Storage Instruction: | Store at 4°C for 12 months Protect from light Do not freeze |
Gene Symbol: | LY6H |
Gene ID: | 4062 |
Uniprot ID: | LY6H_HUMAN |
Function | Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons. |
Protein Name | Lymphocyte Antigen 6hLy-6h |
Database Links | Reactome: R-HSA-163125 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
Alternative Antibody Names | Anti-Lymphocyte Antigen 6h antibodyAnti-Ly-6h antibodyAnti-LY6H antibody |
Information sourced from Uniprot.org