Anti-LY6H antibody [12G7] {APC} (STJA0028917)

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STJA0028917
£310.50 - £472.50
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Host: Mouse
Applications: ELISA/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Lymphocyte antigen 6h is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 12G7
Conjugation: APC
Isotype: IgG2ak
Formulation: 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Purification: Purified
Concentration: 0.5 mg/mL
Storage Instruction: Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol: LY6H
Gene ID: 4062
Uniprot ID: LY6H_HUMAN
Function Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.
Protein Name Lymphocyte Antigen 6h
Ly-6h
Database Links Reactome: R-HSA-163125
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Lymphocyte Antigen 6h antibody
Anti-Ly-6h antibody
Anti-LY6H antibody

Information sourced from Uniprot.org