Anti-LSM3 antibody (1-102) (STJ115155)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LSM3 (1-102) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LSM3 |
| Gene ID | 27258 |
| Uniprot ID | LSM3_HUMAN |
| Immunogen Region | 1-102 |
| Immunogen Sequence | MADDVDQQQTTNTVEEPLDL IRLSLDERIYVKMRNDRELR GRLHAYDQHLNMILGDVEET VTTIEIDEETYEEIYKSTKR NIPMLFVRGDGVVLVAPPLR VG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-102 of human LSM3 (NP_055278.1). |
Additional Info
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. |
| Protein Name | U6 Snrna-Associated Sm-Like Protein Lsm3 |
| Database Links | Reactome: R-HSA-430039Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U6 Snrna-Associated Sm-Like Protein Lsm3 antibodyAnti-LSM3 antibodyAnti-MDS017 antibody |
Information sourced from Uniprot.org