| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LSM10 (1-123) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LSM10 |
| Gene ID: |
84967 |
| Uniprot ID: |
LSM10_HUMAN |
| Immunogen Region: |
1-123 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-123 of human LSM10 (NP_116270.1). |
| Immunogen Sequence: |
MAVSHSVKERTISENSLIIL LQGLQGRVTTVDLRDESVAH GRIDNVDAFMNIRLAKVTYT DRWGHQVKLDDLFVTGRNVR YVHIPDDVNITSTIEQQLQI IHRVRNFGGKGQGRWEFPPK NCK |
| Post Translational Modifications | Not methylated. Methylation is not necessary for interaction with SMN. |
| Function | Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. |
| Protein Name | U7 Snrna-Associated Sm-Like Protein Lsm10 |
| Database Links | Reactome: R-HSA-111367Reactome: R-HSA-73856Reactome: R-HSA-77588 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-U7 Snrna-Associated Sm-Like Protein Lsm10 antibodyAnti-LSM10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
