| Tissue Specificity | Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others. |
| Post Translational Modifications | Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. |
| Function | Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. |
| Protein Name | Adhesion G Protein-Coupled Receptor L2Calcium-Independent Alpha-Latrotoxin Receptor 2Cirl-2Latrophilin Homolog 1Latrophilin-2Lectomedin-1 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor L2 antibodyAnti-Calcium-Independent Alpha-Latrotoxin Receptor 2 antibodyAnti-Cirl-2 antibodyAnti-Latrophilin Homolog 1 antibodyAnti-Latrophilin-2 antibodyAnti-Lectomedin-1 antibodyAnti-ADGRL2 antibodyAnti-KIAA0786 antibodyAnti-LEC1 antibodyAnti-LPHH1 antibodyAnti-LPHN2 antibody |
Information sourced from Uniprot.org
