Anti-LPCAT4 antibody (345-524) (STJ116528)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LPCAT4 (345-524) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LPCAT4 |
| Gene ID | 254531 |
| Uniprot ID | LPCT4_HUMAN |
| Immunogen Region | 345-524 |
| Immunogen Sequence | AGAEPGRSRMISQEEFARQL QLSDPQTVAGAFGYFQQDTK GLVDFRDVALALAALDGGRS LEELTRLAFELFAEEQAEGP NRLLYKDGFSTILHLLLGSP HPAATALHAELCQAGSSQGL SLCQFQNFSLHDPLYGKLFS TYLRPPHTSRGTSQTPNASS PGNPTALANGTVQAPKQKGD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 345-524 of human LPCAT4 (NP_705841.2). |
Additional Info
| Tissue Specificity | Widely expressed with predominant level in brain. |
| Function | Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates.converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors. |
| Protein Name | Lysophospholipid Acyltransferase Lpcat41-Acylglycerol-3-Phosphate O-Acyltransferase 71-Agp Acyltransferase 71-Agpat 71-Acylglycerophosphocholine O-Acyltransferase1-Acylglycerophosphoserine O-Acyltransferase1-Alkenylglycerophosphoethanolamine O-Acyltransferase1-Alkylglycerophosphocholine O-AcetyltransferaseAcyltransferase-Like 3Lysophosphatidylcholine Acyltransferase 4Lysophosphatidylethanolamine Acyltransferase 2Plasmalogen Synthase |
| Database Links | Reactome: R-HSA-1482788Reactome: R-HSA-1482801Reactome: R-HSA-1482839Reactome: R-HSA-1482925Reactome: R-HSA-1483166 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Lysophospholipid Acyltransferase Lpcat4 antibodyAnti-1-Acylglycerol-3-Phosphate O-Acyltransferase 7 antibodyAnti-1-Agp Acyltransferase 7 antibodyAnti-1-Agpat 7 antibodyAnti-1-Acylglycerophosphocholine O-Acyltransferase antibodyAnti-1-Acylglycerophosphoserine O-Acyltransferase antibodyAnti-1-Alkenylglycerophosphoethanolamine O-Acyltransferase antibodyAnti-1-Alkylglycerophosphocholine O-Acetyltransferase antibodyAnti-Acyltransferase-Like 3 antibodyAnti-Lysophosphatidylcholine Acyltransferase 4 antibodyAnti-Lysophosphatidylethanolamine Acyltransferase 2 antibodyAnti-Plasmalogen Synthase antibodyAnti-LPCAT4 antibodyAnti-AGPAT7 antibodyAnti-AYTL3 antibodyAnti-LPEAT2 antibody |
Information sourced from Uniprot.org