• Western blot analysis of extracts of BxPC-3 cells, using LOXL4 antibody (STJ115097) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-LOXL4 antibody (25-280) (STJ115097)

SKU:
STJ115097

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LOXL4 (25-280) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LOXL4
Gene ID: 84171
Uniprot ID: LOXL4_HUMAN
Immunogen Region: 25-280
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human LOXL4 (NP_115587.6).
Immunogen Sequence: QSLGTTKLRLVGPESKPEEG RLEVLHQGQWGTVCDDNFAI QEATVACRQLGFEAALTWAH SAKYGQGEGPIWLDNVRCVG TESSLDQCGSNGWGVSDCSH SEDVGVICHPRRHRGYLSET VSNALGPQGRRLEEVRLKPI LASAKQHSPVTEGAVEVKYE GHWRQVCDQGWTMNNSRVVC GMLGFPSEVPVDSHYYRKVW DLKMRDPKSRLKSLTNKNSF WIHQVTCLGTEPHMANCQV
Tissue Specificity Expressed in many tissues, the highest levels among the tissues studied being in the skeletal muscle, testis and pancreas. Expressed in cartilage.
Post Translational Modifications The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
Function May modulate the formation of a collagenous extracellular matrix.
Protein Name Lysyl Oxidase Homolog 4
Lysyl Oxidase-Like Protein 4
Lysyl Oxidase-Related Protein C
Database Links Reactome: R-HSA-1566948
Reactome: R-HSA-2243919
Cellular Localisation Secreted
Extracellular Space
Alternative Antibody Names Anti-Lysyl Oxidase Homolog 4 antibody
Anti-Lysyl Oxidase-Like Protein 4 antibody
Anti-Lysyl Oxidase-Related Protein C antibody
Anti-LOXL4 antibody
Anti-LOXC antibody

Information sourced from Uniprot.org

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