Host: |
Rabbit |
Applications: |
WB/IF/ICC/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
LORICRIN |
Gene ID: |
4014 |
Uniprot ID: |
LORI_HUMAN |
Immunogen Region: |
1-100 |
Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LORICRIN (NP_000418.2). |
Immunogen Sequence: |
MSYQKKQPTPQPPVDCVKTS GGGGGGGGSGGGGCGFFGGG GSGGGSSGSGCGYSGGGGYS GGGCGGGSSGGGGGGGIGGC GGGSGGSVKYSGGGGSSGGG |
Post Translational Modifications | Substrate of transglutaminases. Some glutamines and lysines are cross-linked to other loricrin molecules and to SPRRs proteins. Contains inter- or intramolecular disulfide-bonds. |
Function | Major keratinocyte cell envelope protein. |
Protein Name | Loricrin |
Database Links | Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
Cellular Localisation | CytoplasmNucleusNucleoplasm |
Alternative Antibody Names | Anti-Loricrin antibodyAnti-LORICRIN antibodyAnti-LOR antibodyAnti-LRN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance