Anti-LNK/SH2B3 antibody (N-Term) (STJ70582)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-LNK/SH2B3 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 70kDa band observed in lysates of cell line MOLT4 (calculated MW of 63.2kDa according to NP_005466.1). In transfected HEK293 transiently expressing SH2B3 a band of approx. 65kDa |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SH2B3 |
| Gene ID | 10019 |
| Uniprot ID | SH2B3_HUMAN |
| Accession Number | NP_005466.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | NGPALQPSSPC |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated by LCK. |
| Function | Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. |
| Protein Name | Sh2b Adapter Protein 3Lymphocyte Adapter ProteinLymphocyte-Specific Adapter Protein LnkSignal Transduction Protein Lnk |
| Database Links | Reactome: R-HSA-1433559Reactome: R-HSA-9706369Reactome: R-HSA-983231 |
| Alternative Antibody Names | Anti-Sh2b Adapter Protein 3 antibodyAnti-Lymphocyte Adapter Protein antibodyAnti-Lymphocyte-Specific Adapter Protein Lnk antibodyAnti-Signal Transduction Protein Lnk antibodyAnti-SH2B3 antibodyAnti-LNK antibody |
Information sourced from Uniprot.org