Host: | Rabbit |
Applications: | ELISA/IP/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-LMNB1 (450-500) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Biotin |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.5-1.5 µg/µl |
Dilution Range: | WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200IHC: 1:50-1:150 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | LMNB1 |
Gene ID: | 4001 |
Uniprot ID: | LMNB1_HUMAN |
Immunogen Region: | 450-500 |
Immunogen: | Synthetic peptide taken within amino acid region 450-500 on human Lamin-B1 protein. |
Post Translational Modifications | B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. |
Function | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. |
Protein Name | Lamin-B1 |
Database Links | Reactome: R-HSA-1221632Reactome: R-HSA-2559584Reactome: R-HSA-2980766Reactome: R-HSA-2995383Reactome: R-HSA-352238Reactome: R-HSA-4419969Reactome: R-HSA-8862803Reactome: R-HSA-8950505Reactome: R-HSA-9013405Reactome: R-HSA-9035034 |
Cellular Localisation | Nucleus Lamina |
Alternative Antibody Names | Anti-Lamin-B1 antibodyAnti-LMNB1 antibodyAnti-LMN2 antibodyAnti-LMNB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance