| Host: |
Mouse |
| Applications: |
FC/IF/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Liver antigen is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
EP-2 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2bk |
| Formulation: |
PBS with 0.02% Sodium Azide. |
| Purification: |
Affinity purified from tissue culture. |
| Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: |
Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30 min at RT; an appropriate antigen retrieval method for staining of formalin-fixed tissues has not been established to date |
| Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: |
CDC42EP2 |
| Gene ID: |
10435 |
| Uniprot ID: |
BORG1_HUMAN |
| Immunogen: |
A BALB/c mouse was immunized with HEB-3B human hepatocarcinoma cells. Fusion partner: NS-1. |
| Tissue Specificity | Highly expressed in the heart. Weakly expressed in the pancreas and liver. |
| Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. |
| Protein Name | Cdc42 Effector Protein 2Binder Of Rho Gtpases 1 |
| Database Links | Reactome: R-HSA-5687128Reactome: R-HSA-9013148Reactome: R-HSA-9013406 |
| Cellular Localisation | Endomembrane SystemPeripheral Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Cdc42 Effector Protein 2 antibodyAnti-Binder Of Rho Gtpases 1 antibodyAnti-CDC42EP2 antibodyAnti-BORG1 antibodyAnti-CEP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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