• Western blot with Anti-LILRB3 Antibody (STJ501603) with peptide.

Anti-LILRB3 antibody (800-841) (STJ501603)

SKU:
STJ501603-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LILRB3 (800-841) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.74 µg/µl
Dilution Range: WB: 1:500
DB: 1:20, 000
ELISA: 1:20, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Lilrb3
Gene ID: 18733
Uniprot ID: LIRB3_MOUSE
Immunogen Region: 800-841
Immunogen: Synthetic peptide taken within amino acid region 800-841 on mouse LILRB3 protein.
Tissue Specificity Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells.
Post Translational Modifications Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-794 and Tyr-824 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2.
Function May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3
Lir-3
Leukocyte Immunoglobulin-Like Receptor 3
Cell-Surface Glycoprotein P91
Paired Immunoglobulin-Like Receptor B
Pir-B
Database Links Reactome: R-MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 antibody
Anti-Lir-3 antibody
Anti-Leukocyte Immunoglobulin-Like Receptor 3 antibody
Anti-Cell-Surface Glycoprotein P91 antibody
Anti-Paired Immunoglobulin-Like Receptor B antibody
Anti-Pir-B antibody
Anti-Lilrb3 antibody
Anti-Pirb antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance