| Host: |
Rabbit |
| Applications: |
ELISA/WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LILRB3 (800-841) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.74 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:20, 000ELISA: 1:20, 000IP: 1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Lilrb3 |
| Gene ID: |
18733 |
| Uniprot ID: |
LIRB3_MOUSE |
| Immunogen Region: |
800-841 |
| Immunogen: |
Synthetic peptide taken within amino acid region 800-841 on mouse LILRB3 protein. |
| Tissue Specificity | Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells. |
| Post Translational Modifications | Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-794 and Tyr-824 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2. |
| Function | May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). |
| Protein Name | Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3Lir-3Leukocyte Immunoglobulin-Like Receptor 3Cell-Surface Glycoprotein P91Paired Immunoglobulin-Like Receptor BPir-B |
| Database Links | Reactome: R-MMU-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 antibodyAnti-Lir-3 antibodyAnti-Leukocyte Immunoglobulin-Like Receptor 3 antibodyAnti-Cell-Surface Glycoprotein P91 antibodyAnti-Paired Immunoglobulin-Like Receptor B antibodyAnti-Pir-B antibodyAnti-Lilrb3 antibodyAnti-Pirb antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
