• Immunohistochemistry of baboon spleen with Anti-LILRB3 primary antibody (STJ501604) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-LILRB3 antibody (580-631) (STJ501604)

SKU:
STJ501604-100

£441.50
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LILRB3 (580-631) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.74 µg/µl
Dilution Range: WB: 1:500
DB: 1:20, 000
ELISA: 1:20, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: LILRB3
Gene ID: 102725035/107987462
Uniprot ID: LIRB3_HUMAN
Immunogen Region: 580-631
Specificity: This antibody will detect all three isoforms of human LILRB3 protein.
Immunogen: Synthetic peptide taken within amino acid region 580-631 on human LILRB3 protein.
Tissue Specificity Detected in monocytes and B-cells.
Post Translational Modifications Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2.
Function May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3
Lir-3
Leukocyte Immunoglobulin-Like Receptor 3
Cd85 Antigen-Like Family Member A
Immunoglobulin-Like Transcript 5
Ilt-5
Monocyte Inhibitory Receptor Hl9
Cd Antigen Cd85a
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 antibody
Anti-Lir-3 antibody
Anti-Leukocyte Immunoglobulin-Like Receptor 3 antibody
Anti-Cd85 Antigen-Like Family Member A antibody
Anti-Immunoglobulin-Like Transcript 5 antibody
Anti-Ilt-5 antibody
Anti-Monocyte Inhibitory Receptor Hl9 antibody
Anti-Cd Antigen Cd85a antibody
Anti-LILRB3 antibody
Anti-ILT5 antibody
Anti-LIR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance