| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LIF |
| Gene ID: | 3976 |
| Uniprot ID: | LIF_HUMAN |
| Immunogen Region: | 23-202 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 23-202 of human LIF (NP_002300.1). |
| Immunogen Sequence: | SPLPITPVNATCAIRHPCHN NLMNQIRSQLAQLNGSANAL FILYYTAQGEPFPNNLDKLC GPNVTDFPPFHANGTEKAKL VELYRIVVYLGTSLGNITRD QKILNPSALSLHSKLNATAD ILRGLLSNVLCRLCSKYHVG HVDVTYGPDTSGKDVFQKKK LGCQLLGKYKQIIAVLAQAF |
| Function | LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
| Protein Name | Leukemia Inhibitory Factor Lif Differentiation-Stimulating Factor D Factor Melanoma-Derived Lpl Inhibitor Mlpli Emfilermin |
| Database Links | Reactome: R-HSA-6783783 Reactome: R-HSA-6785807 Reactome: R-HSA-6788467 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Leukemia Inhibitory Factor antibody Anti-Lif antibody Anti-Differentiation-Stimulating Factor antibody Anti-D Factor antibody Anti-Melanoma-Derived Lpl Inhibitor antibody Anti-Mlpli antibody Anti-Emfilermin antibody Anti-LIF antibody Anti-HILDA antibody |
Information sourced from Uniprot.org