| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Leucine-rich glioma-inactivated protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LGI1 |
| Gene ID: |
9211 |
| Uniprot ID: |
LGI1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of LGI1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human LGI1 |
| Post Translational Modifications | Glycosylated. |
| Function | Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival. |
| Protein Name | Leucine-Rich Glioma-Inactivated Protein 1Epitempin-1 |
| Database Links | Reactome: R-HSA-5682910 |
| Cellular Localisation | SecretedSynapseCytoplasmIsoform 1: Golgi ApparatusIsoform 2: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Leucine-Rich Glioma-Inactivated Protein 1 antibodyAnti-Epitempin-1 antibodyAnti-LGI1 antibodyAnti-EPT antibodyAnti-UNQ775 antibodyAnti-PRO1569 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
