• Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using LEG8 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from NIH/3T3 cells, using LEG8 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of 3T3 cells using Galectin-8 Polyclonal Antibody diluted at 1：1000

Anti-LGALS8 antibody (61-110 aa) (STJ93205)

SKU:
STJ93205

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Galectin-8 (61-110 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:100-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LGALS8
Gene ID: 3964
Uniprot ID: LEG8_HUMAN
Immunogen Region: 61-110 aa
Specificity: Galectin-8 Polyclonal Antibody detects endogenous levels of Galectin-8 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human LEG8 at the amino acid range 61-110
Function Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane.these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.
Protein Name Galectin-8
Gal-8
Po66 Carbohydrate-Binding Protein
Po66-Cbp
Prostate Carcinoma Tumor Antigen 1
Pcta-1
Cellular Localisation Cytoplasmic Vesicle
Cytoplasm
Cytosol
Alternative Antibody Names Anti-Galectin-8 antibody
Anti-Gal-8 antibody
Anti-Po66 Carbohydrate-Binding Protein antibody
Anti-Po66-Cbp antibody
Anti-Prostate Carcinoma Tumor Antigen 1 antibody
Anti-Pcta-1 antibody
Anti-LGALS8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance