Anti-LEPROT antibody (STJA0008767)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human LEPROT
General Information
| Short Description | Rabbit polyclonal anti-Leptin receptor gene-related protein for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LEPROT |
| Gene ID | 54741 |
| Uniprot ID | OBRG_HUMAN |
| Immunogen | Synthesized peptide derived from human LEPROT |
| Specificity | This antibody detects endogenous levels of LEPROT at Human, Mouse, Rat |
Additional Info
| Function | Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. |
| Protein Name | Leptin Receptor Gene-Related ProteinEndospanin-1Leptin Receptor Overlapping Transcript ProteinOb-R Gene-Related ProteinOb-Rgrp |
| Database Links | |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinEndosome Membrane |
| Alternative Antibody Names | Anti-Leptin Receptor Gene-Related Protein antibodyAnti-Endospanin-1 antibodyAnti-Leptin Receptor Overlapping Transcript Protein antibodyAnti-Ob-R Gene-Related Protein antibodyAnti-Ob-Rgrp antibodyAnti-LEPROT antibodyAnti-LEPR antibodyAnti-OBR antibody |
Information sourced from Uniprot.org