| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Leptin receptor gene-related protein is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LEPROT |
| Gene ID: | 54741 |
| Uniprot ID: | OBRG_HUMAN |
| Specificity: | This antibody detects endogenous levels of LEPROT at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human LEPROT |
| Function | Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. |
| Protein Name | Leptin Receptor Gene-Related ProteinEndospanin-1Leptin Receptor Overlapping Transcript ProteinOb-R Gene-Related ProteinOb-Rgrp |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinEndosome Membrane |
| Alternative Antibody Names | Anti-Leptin Receptor Gene-Related Protein antibodyAnti-Endospanin-1 antibodyAnti-Leptin Receptor Overlapping Transcript Protein antibodyAnti-Ob-R Gene-Related Protein antibodyAnti-Ob-Rgrp antibodyAnti-LEPROT antibodyAnti-LEPR antibodyAnti-OBR antibody |
Information sourced from Uniprot.org
