Anti-LEMD3 antibody (61-111 aa) (STJ195757)

SKU:
STJ195757
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Inner nuclear membrane protein Man1 (61-111 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:LEMD3
Gene ID:23592
Uniprot ID:MAN1_HUMAN
Immunogen:Synthesized peptide derived from the human MAN1 at the amino acid range 61-111
Immunogen Region:61-111 aa
Specificity:This antibody detects endogenous levels of MAN1 at Human/Mouse
Function Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.
Protein Name Inner Nuclear Membrane Protein Man1
Lem Domain-Containing Protein 3
Database Links Reactome: R-HSA-2980766
Reactome: R-HSA-2995383
Reactome: R-HSA-4419969
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013405
Reactome: R-HSA-9013408
Reactome: R-HSA-9013423
Reactome: R-HSA-9696264
Reactome: R-HSA-9696270
Reactome: R-HSA-9696273
Cellular Localisation Nucleus Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Inner Nuclear Membrane Protein Man1 antibody
Anti-Lem Domain-Containing Protein 3 antibody
Anti-LEMD3 antibody
Anti-MAN1 antibody

Information sourced from Uniprot.org