Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Low-density lipoprotein receptor class A domain-containing protein 3 (37-86 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | LDLRAD3 |
Gene ID: | 143458 |
Uniprot ID: | LRAD3_HUMAN |
Immunogen Region: | 37-86 aa |
Specificity: | LDLRAD3 Polyclonal Antibody detects endogenous levels of LDLRAD3 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human LDLRAD3 at the amino acid range 37-86 |
Function | May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. May regulate ITCH and NEDD4 E3 ligase activity and degradation. (Microbial infection) Acts as a receptor for Venezuelan equine encephalitis virus. |
Protein Name | Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 3Ldlr Class A Domain-Containing Protein 3 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 3 antibodyAnti-Ldlr Class A Domain-Containing Protein 3 antibodyAnti-LDLRAD3 antibodyAnti-LRAD3 antibody |
Information sourced from Uniprot.org