Anti-Lck-interacting molecule antibody [LIME-06] (STJ16100292)

Name: Anti-Lck-interacting molecule antibody [LIME-06] (STJ16100292)
SKU: STJ16100292-01
Price: 773.49 USD
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG1

ImmunogenBacterially expressed intracellular fragment corresponding to aa 141-295 of human LIME.

STJ16100292-01

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Mouse monoclonal anti-Lck-interacting molecule for use in IP and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IP/FC
Host	Mouse
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	LIME-06
Isotype	IgG1
Conjugation	Unconjugated
Concentration	1 mg/mL
Formulation	Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage Instruction	Store at 2-8°C for up to 1-year, upon receipt.

Gene Symbol	LIME1
Gene ID	54923
Uniprot ID	LIME1_HUMAN
Immunogen	Bacterially expressed intracellular fragment corresponding to aa 141-295 of human LIME.

Tissue Specificity	Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level).
Post Translational Modifications	Palmitoylation of Cys-28 and Cys-31 is required for raft targeting. Phosphorylated on tyrosines upon TCR activation and/or CD4 coreceptor stimulation, or upon BCR stimulation.which leads to the recruitment of SH2-containing proteins.
Function	Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules.
Protein Name	Lck-Interacting Transmembrane Adapter 1 Lck-Interacting Membrane Protein Lck-Interacting Molecule
Database Links
Cellular Localisation	Cell Membrane Single-Pass Type Iii Membrane Protein Present In Lipid Rafts Recruited To The Immunological Synapse Upon Conjugation Of T-Cell With Antigen-Presenting Cell
Alternative Antibody Names	Anti-Lck-Interacting Transmembrane Adapter 1 antibody Anti-Lck-Interacting Membrane Protein antibody Anti-Lck-Interacting Molecule antibody Anti-LIME1 antibody Anti-LIME antibody Anti-LP8067 antibody

Information sourced from Uniprot.org