| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Lymphocyte transmembrane adapter 1 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LAX1 |
| Gene ID: | 54900 |
| Uniprot ID: | LAX1_HUMAN |
| Immunogen Region: | 30-110 aa |
| Specificity: | LAX1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 30-110 |
| Post Translational Modifications | Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation.which leads to the recruitment of GRB2, PIK3R1 and GRAP2. |
| Function | Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells. |
| Protein Name | Lymphocyte Transmembrane Adapter 1 Linker For Activation Of X Cells Membrane-Associated Adapter Protein Lax |
| Cellular Localisation | Cell Membrane Single-Pass Type Iii Membrane Protein |
| Alternative Antibody Names | Anti-Lymphocyte Transmembrane Adapter 1 antibody Anti-Linker For Activation Of X Cells antibody Anti-Membrane-Associated Adapter Protein Lax antibody Anti-LAX1 antibody Anti-LAX antibody |
Information sourced from Uniprot.org